Frequently Asked Questions (FAQs) - PENNSAID - Official Site

Frequently Asked Questions (FAQs)

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How do I know I’m getting the right amount of PENNSAID 2%?

PENNSAID 2% is supplied in a convenient metered-dose pump. Two pumps, two times daily give you the exact amount you need. There is no measuring needed. Do not use more than the recommended dose.

How much PENNSAID 2% can I use each day?

Always follow your doctor’s instructions on how to use PENNSAID 2%. The recommended dose is 2 pumps per affected knee, 2 times a day. Do not use more than the recommended dose.

If I’m overweight, do I need to apply more than 2 pumps,
2 times a day?

No. The PENNSAID 2% daily dose is not based on weight. Simply apply PENNSAID 2% at the recommended dose: 2 pumps per affected knee, 2 times a day.

If I have pain only in the front of my knee, do I still need to put PENNSAID 2% on all 4 sides of my knee?

Always apply PENNSAID 2% to all 4 sides of the knee(s). Since OA of the knee affects the entire knee, applying PENNSAID 2% to just the top of the knee could lessen the pain relief you experience.

How long does it take for PENNSAID 2% to dry?

Drying times may vary. Your knee should be dry to the touch within a short period of time.

How long after applying PENNSAID 2% should I wait to apply a heat compress?

Do not use heating pads or apply bandages to your knee(s) after using PENNSAID 2%. Heat is often used to loosen stiffened joints. However, when heat is combined with PENNSAID 2%, it could change how PENNSAID 2% is absorbed.

Will lotions or other medications be pulled into my skin when I apply PENNSAID 2%?

In medical studies, there were no reports of substances being absorbed after use of PENNSAID 2%. Just be sure to always wash your hands before and after applying PENNSAID 2%. Your knee should be clean and dry before you apply PENNSAID 2%. Wait until the area is completely dry before applying sunscreen, insect repellent, cosmetics, topical medications, or other substances.

What other pain relief products can I use with PENNSAID 2%?

When using PENNSAID 2%, avoid using any other nonsteroidal anti-inflammatory drugs, or NSAIDs. Some examples of NSAIDs are ibuprofen and naproxen. Also, NSAIDs may be present in over-the-counter medications for treatment of colds, fever, or insomnia; refer to the label of over-the-counter medications you are taking or ask your pharmacist. Talk to your doctor about which other medicines you can take while using PENNSAID 2%.

Can I still use PENNSAID 2% if I take blood thinners?

When you take a blood thinner and an NSAID, you are at a higher risk of having a serious stomach bleed than someone who takes only one of these. Tell your doctor about all of the prescription and over-the-counter medicines you are taking, including vitamins. Only your doctor can decide if PENNSAID 2% is right for you.

For any other questions, please contact Product Support at 1-866-479-6742.

Indication, Usage, and Important Safety Information

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What is PENNSAID® (diclofenac sodium topical solution) 2% w/w?

PENNSAID® (diclofenac sodium topical solution) 2% w/w is a nonsteroidal anti-inflammatory drug (NSAID) applied to the skin, used for treating the pain of osteoarthritis of the knee(s).

IMPORTANT SAFETY INFORMATION

PENNSAID can cause serious side effects. Stop taking PENNSAID and call your doctor or go to your emergency department right away if you get:

  • Difficulty breathing, swelling of the face or throat. These could be signs of a serious allergic reaction.
  • Chest pain, shortness of breath, weakness in one part or side of your body, or slurring of speech. These could be signs of a serious blood clotting event.
  • Upper stomach pain, upset stomach, black, tarry stools, or vomiting of blood. These could be signs of an esophagus, stomach or intestinal ulcer, bleed, or tear. Note: if you are also taking low-dose aspirin, you are at increased risk for esophagus, stomach or intestinal bleeding.
  • Nausea, more tired or weaker than usual, itching, yellowing of the skin or eyes, right upper abdomen tenderness, and “flu-like” symptoms. These could be signs of a liver problem.
  • Shortness of breath, unexplained weight gain, or swelling of the arms, legs, hand or feet. These could be signs of a serious heart problem.
  • Any type of rash. This could be a sign of a serious skin reaction.

These are not all of the possible side effects of PENNSAID. Please talk to your doctor if you experience any symptoms that bother you or that
do not go away.

What is the most important information I should know about PENNSAID?

  • NSAIDs cause an increased risk of serious blood clotting events, including heart attack and stroke, which can kill you. This risk may occur early in treatment and may increase with longer use. To minimize the potential for increased risk of serious heart events while being treated with an NSAID, use the lowest effective dose for the shortest duration possible.
  • NSAIDs cause an increased risk of serious esophagus, stomach and intestine events including bleeding, ulcers, and tears, which can kill you. These events can occur at any time during use and without warning symptoms. Elderly patients and patients with a history of ulcer disease or stomach or intestine bleeding are at greater risk for serious esophagus, stomach and intestine events.

Who should not use PENNSAID?

  • DO NOT USE PENNSAID if you:
    • are in the hospital for a certain heart surgery called coronary artery bypass graft surgery.
    • know you are allergic to diclofenac or any other ingredient of PENNSAID.
    • have experienced asthma, hives, or allergic-type reactions after taking aspirin or other NSAIDs. Serious allergic reactions to NSAIDs, including death, have been reported in such patients.

How should I use PENNSAID?

PENNSAID is applied directly to the front, back, and sides of your knee(s). Avoid contact of PENNSAID with the eyes, nose and mouth. If eye contact occurs, immediately wash out the eye with water and contact your health care provider if irritation persists for more than an hour. Avoid skin-to-skin contact between other people and the knee(s) to which PENNSAID was applied until the knee(s) is completely dry. DO NOT apply PENNSAID to open wounds, infections or rashes, shower for at least 30 minutes after applying PENNSAID or wear clothing over the PENNSAID treated knee(s) until the treated knee(s) is dry. DO wash and dry hands before and after use, protect your treated knee(s) from natural or artificial sunlight, and wait until the treated knee(s) is completely dry before applying sunscreen, insect repellant, lotion, moisturizer, cosmetics, or other topical medication.

What are the possible side effects of PENNSAID?

The most common side effects of PENNSAID are application site reactions, such as dryness, peeling, redness, itching, pain, skin hardening, rash, blisters, and scabbing. Other side effects are bladder infection, bruising, sinus congestion, nausea, upset stomach, stomach pain, gas, constipation, and diarrhea.

What other medications might interact with PENNSAID?

Avoid using PENNSAID while taking other NSAIDs unless your doctor says it is OK. NSAIDs may be present in over-the-counter medications for treatment of colds, fever, or insomnia; refer to the label of over-the-counter medications you are taking or ask your pharmacist. Do not use PENNSAID and low-dose aspirin until you talk to your health care provider. Tell your doctor about all of the medicines you take as some medicines can react with NSAIDs and cause serious side effects.

What should I tell my healthcare provider?

Before starting PENNSAID, tell your health care provider if you have a history of ulcer disease or esophagus, stomach or intestine bleeding, liver or kidney problems, high blood pressure, asthma, or are pregnant, trying to become pregnant or are breast feeding. Also tell your doctor about all of the medicines you take, including prescription or over-the-counter medicines, vitamins or herbal supplements. Do not start taking new medicines without talking to your health care provider first.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit http://www.fda.gov/medwatch, or call 1-800-FDA-1088. You may also contact the Horizon Pharma Medical Information Department toll-free at 1-866-479-6742 or medicalinformation@horizonpharma.com.

The risk information provided here is not comprehensive. To learn more, talk about PENNSAID 2% with your healthcare provider or pharmacist. Click here for the Prescribing Information and Medication Guide or call 1-866-479-6742.